Researchers may have found the reason why so many experimental Alzheimer's drugs have failed. Many of these drugs seek to reduce the size and number of plaques of tangled amyloid beta proteins that damage the brains of people with Alzheimer's. New research published in the Journal of Biological Chemistry by scientists at UCLA show that amyloid beta proteins start clumping together in oligomers long before they form plaques. Anti-Alzheimer's drugs don't affect these oligomers, which have a different structure and may be the real culprit of disease symptoms.
More info: http://www.jbc.org/content/288/26/18684
Fantastic.
ReplyDeleteWould this be similar in MS and Parkinson's?
ReplyDeletehave an question and i wish it take attention by yours.. how can brain cells kept save for patients who used to take a cure like diabetes patients, high pressure patients, ells.. you know that this effects directly on nerve system and brain cells which causes some confusion and forgetting cases in them
ReplyDeleteMore sports may help retard onset of Parkinson's. However most difficult to model yet is Alzheimer's
ReplyDeletethanks to all
ReplyDelete