Decellularization

Decellularization

What is decellularization?
Decellularization is the process of removing all of the cells from an organ leaving only the extracellular matrix, the framework between the cells, intact.

Process
In brief, the first step involves an application of specialized detergent known to be inefficient solubilized without affecting the integrity of the protein in the tissue.
Then a recombinant endonuclease is used to degrade nucleic acids .
The second step relates to ensuring decellularization is complete.
Step three is meant to preserve, protect, and hold the tissue in similar body conditions, ready to be utilized.

Know more:
http://en.wikipedia.org/wiki/Decellularization

In April 2011 Dr. Doris Taylor and her team at the University of Minnesota used adult human stem cells to create a human heart (see picture). This was from a heart stripped of its cells, leaving behind a tough protein skeleton known as a "ghost heart". This was then coated with adult human stem cells.

More about this:
http://www.lifesitenews.com/news/breakthrough-new-heart-grown-using-adult-stem-cells

Image via Texas Heart Institute