Friday, 30 November 2018

InSight's first image from Mars


InSight's first image from Mars
Am I excited about this new Mars mission? Woohoo...I am beyond excited.
I mean, look at this stracciatella bonbon :)

This is the first image taken by NASA’s InSight lander on the surface of Mars. The instrument context camera (ICC) mounted below the lander deck obtained this image on Nov. 26, 2018, shortly after landing. The transparent lens cover was still in place to protect the lens from any dust kicked up during landing.

Credit
NASA/JPL-Caltech
https://mars.nasa.gov/resources/22159/insights-first-image-from-mars/

#space #NASA #MARS #InSight #exploration #science #universe

SMD Spacecraft Fleet


SMD Spacecraft Fleet
NASA Science missions circle Earth, the Sun, the Moon, Mars and many other destinations within our solar system, including spacecraft that look out even further into our universe. The Science Fleet depicts the scope of NASA's activity and how their missions have traveled throughout the solar system.

Credit
NASA/GSFC

#NASA #space #universe #science

Opposing Solar Prominences


Opposing Solar Prominences
Two solar prominences, directly at opposite sides of the Sun, rose up, twisted around, and fell apart at roughly the same time over a 26-hour period (Nov. 12-13, 2018). Prominences are cooler clouds of plasma suspended above the Sun by powerful magnetic forces. Although prominences are fairly common, it is uncommon to see two of them, about the same size, diametrically opposed to each other and lasting just about the same time. The images were taken in a wavelength of extreme ultraviolet light.

Credit: Solar Dynamics Observatory, NASA.
https://sdo.gsfc.nasa.gov/

#universe #NASA #space #sun #prominences #science

A new way to watch brain activity in action


A new way to watch brain activity in action
It’s a neuroscientist’s dream: being able to track the millions of interactions among brain cells in animals that move about freely, behaving as they would under natural circumstances. New technology developed at The Rockefeller University represents a big step toward realizing that goal.

The invention, reported in Nature Methods, is expected to give researchers a dynamic tool to study the brain’s role in various behaviors. Although designed for use on mice, information gleaned from it could someday shed light on neuronal activity in humans as well, says Alipasha Vaziri, who led the technology’s development as head of the Laboratory of Neurotechnology and Biophysics. For example, it might allow us to better understand the neuronal basis of brain disorders such as autism and schizophrenia.

Vaziri says the tool provides an opening to an exciting range of discoveries. As an animal moves about its environment, for instance, some neurons direct spatial navigation while others receive sensory feedback from changes to the body’s position or the visual system. “Until now, no one has been able to detect how these different neurons, which can be located at different depths within a volume of brain tissue, dynamically interact with each other in a freely moving rodent,” says Vaziri, an associate professor at Rockefeller. Similarly, the tool can be used to record the interplay among neurons when two animals meet and interact socially.

High-tech headgear
The technology consists of a tiny microscope attached to a mouse’s head and outfitted with a specialized group of lenses called a microlens array. These lenses enable the microscope to capture images from multiple angles and depths on a sensor chip, producing a three-dimensional record of neurons blinking on and off as they communicate with each other through electrochemical impulses. (In the experiments, the mouse neurons are genetically modified to light up when they become activated.) A coaxial cable attached to the top of the microscope transmits the data for recording. The head-mounted gear weighs only four grams, but Vaziri expects that planned modifications will make it even lighter.

Once the microlens array has captured sensor images from within a volume of brain tissue, the next challenge is to process this raw data. Brain tissue is opaque, making it difficult to pinpoint the source of each neuronal light flash. Vaziri’s team solved this problem, which is the result of so-called scattering, by developing a new computer algorithm. “The algorithm utilizes the statistical properties of neurons’ distribution in space and in activity,” Vaziri explains, “while extracting additional information from the scattered emission light. This enables their activity to be simultaneously and faithfully recorded within a volume despite the highly scattering tissue properties.”

The result is a clear image that shows individual neurons flashing in sequence.

Faster, more effective imaging
Vaziri’s lab has previously applied this algorithm, known by the acronym SID, in studies in which the heads of the mice were secured in a fixed position. Their latest research is the first to demonstrate that these inventions can be used together with a tiny microscope called the Miniscope, developed by a collaborating team at the University of California Los Angeles, to measure neuronal activity volumetrically in unconstrained animals.

The technology, if widely adopted, could offer several advantages over two-photon microscopy, a broadly used neuroscience tool. For example, two-photon microscopy records neuronal activity within individual focal planes—thin, virtual “slices” of the sample—that then are combined to create a three-dimensional image. In contrast, Vaziri’s method immediately captures data in three dimensions over an entire volume of tissue, making it faster and more effective.

Vaziri plans to continue developing tools to record neuronal activity in even larger portions of the brain than currently possible, and at higher speeds and resolution. “We hope this work will ultimately lead to a deeper understanding of how the brain processes information underlying the generation of behavior,” he says.

Source:
https://www.rockefeller.edu/news/22576-new-way-watch-brain-activity-action/

Journal article:
https://www.nature.com/articles/s41592-018-0008-0

GIF: A mouse’s hippocampal brain neurons flash on and off as the animal walks around with a microlens array on its head.
Credit: The Rockefeller University

#brainactivity #hippocampus #neurons #animalmodel #neuroscience

The Yogi masters were right – breathing exercises can sharpen your mind


The Yogi masters were right – breathing exercises can sharpen your mind
It has long been claimed by Yogis and Buddhists that meditation and ancient breath-focused practices, such as pranayama, strengthen our ability to focus on tasks. A study by researchers at Trinity College Dublin explains for the first time the neurophysiological link between breathing and attention.

Breath-focused meditation and yogic breathing practices have numerous known cognitive benefits, including increased ability to focus, decreased mind wandering, improved arousal levels, more positive emotions, decreased emotional reactivity, along with many others. To date, however, no direct neurophysiological link between respiration and cognition has been suggested.

The research shows for the first time that breathing – a key element of meditation and mindfulness practices – directly affects the levels of a natural chemical messenger in the brain called noradrenaline. This chemical messenger is released when we are challenged, curious, exercised, focused or emotionally aroused, and, if produced at the right levels, helps the brain grow new connections, like a brain fertilizer. The way we breathe, in other words, directly affects the chemistry of our brains in a way that can enhance our attention and improve our brain health.

The study, carried out by researchers at Trinity College Institute of Neuroscience and the Global Brain Health Institute at Trinity, found that participants who focused well while undertaking a task that demanded a lot of attention had greater synchronization between their breathing patterns and their attention, than those who had poor focus. The authors believe that it may be possible to use breath-control practices to stabilize attention and boost brain health.

Michael Melnychuk, PhD candidate at the Trinity College Institute of Neuroscience, Trinity, and lead author of the study, explained: “Practitioners of yoga have claimed for some 2,500 years, that respiration influences the mind. In our study we looked for a neurophysiological link that could help explain these claims by measuring breathing, reaction time, and brain activity in a small area in the brainstem called the locus coeruleus, where noradrenaline is made. Noradrenaline is an all-purpose action system in the brain. When we are stressed we produce too much noradrenaline and we can’t focus. When we feel sluggish, we produce too little and again, we can’t focus. There is a sweet spot of noradrenaline in which our emotions, thinking and memory are much clearer.”

“This study has shown that as you breathe in locus coeruleus activity is increasing slightly, and as you breathe out it decreases. Put simply this means that our attention is influenced by our breath and that it rises and falls with the cycle of respiration. It is possible that by focusing on and regulating your breathing you can optimize your attention level and likewise, by focusing on your attention level, your breathing becomes more synchronized.”

The research provides deeper scientific understanding of the neurophysiological mechanisms which underlie ancient meditation practices. The findings were recently published in a paper entitled ‘Coupling of respiration and attention via the locus coeruleus: Effects of meditation and pranayama’ in the journal Psychophysiology. Further research could help with the development of non-pharmacological therapies for people with attention compromised conditions such as ADHD and traumatic brain injury and in supporting cognition in older people.

There are traditionally two types of breath-focused practices — those that emphasize focus on breathing (mindfulness), and those that require breathing to be controlled (deep breathing practices such as pranayama). In cases when a person’s attention is compromised, practices which emphasize concentration and focus, such as mindfulness, where the individual focuses on feeling the sensations of respiration but make no effort to control them, could possibly be most beneficial. In cases where a person’s level of arousal is the cause of poor attention, for example drowsiness while driving, a pounding heart during an exam, or during a panic attack, it should be possible to alter the level of arousal in the body by controlling breathing. Both of these techniques have been shown to be effective in both the short and the long term.

Ian Robertson, Co-Director of the Global Brain Health Institute at Trinity and Principal Investigator of the study added: “Yogis and Buddhist practitioners have long considered the breath an especially suitable object for meditation. It is believed that by observing the breath, and regulating it in precise ways—a practice known as pranayama—changes in arousal, attention, and emotional control that can be of great benefit to the meditator are realized. Our research finds that there is evidence to support the view that there is a strong connection between breath-centered practices and a steadiness of mind.”

“Our findings could have particular implications for research into brain ageing. Brains typically lose mass as they age, but less so in the brains of long term meditators. More ‘youthful’ brains have a reduced risk of dementia and mindfulness meditation techniques actually strengthen brain networks. Our research offers one possible reason for this – using our breath to control one of the brain’s natural chemical messengers, noradrenaline, which in the right ‘dose’ helps the brain grow new connections between cells. This study provides one more reason for everyone to boost the health of their brain using a whole range of activities ranging from aerobic exercise to mindfulness meditation."

Source:
https://www.tcd.ie/news_events/articles/the-yogi-masters-were-right-breathing-exercises-can-sharpen-your-mind/8917/

Journal article:
https://onlinelibrary.wiley.com/doi/abs/10.1111/psyp.13091

#meditation #locuscoeruleus #pranayama #noradrenaline #breathing #neuroscience