Heart TransplantationA heart transplant is a surgical procedure performed to remove a damaged or diseased heart and replaces it with a healthy one. The healthy heart comes from a donor who has died. It is the last resort for people with heart failure when all other treatments have failed. The heart failure might have been caused by coronary heart disease, damaged heart valves or heart muscles, congenital heart defects, or viral infections of the heart.
Although heart transplant surgery is a life-saving measure, it has many risks. Careful monitoring, treatment, and regular medical care can prevent or help manage some of these risks.
Heart transplantation continues to be the "gold standard" treatment for end-stage heart failure, and a large number of patients now live 20 years or more after surgery.
Hector Rodriguez Cetina Biefer, MD and Markus J. Wilhelm, MD, from the University Hospital Zurich in Switzerland, led a research team that examined long-term outcomes in 133 patients from their institution who underwent heart transplantation from 1985 to 1991.
Among those patients, 74 (55.6%) survived at least 20 years post-transplantation. The average age at transplant for the 20-year survivors was 43.6 years.
Major causes of death in non-survivors were graft rejection (21%), malignancy (21%), cardiac allograft vasculopathy (an accelerated form of coronary artery disease; 14.5%), and infections (14.5%).
"This study underscores the excellent long-term survival that can be achieved, even among patients who received a transplant in the early 1990s," said Dr. Kirklin. "The fact that over half of patients were alive 20 years later should provide hope and the expectation that a new heart for most patients really is a 'new lease on life.' If patients take care of themselves, they can expect to have many years of good quality of life."
Source:
http://www.ncbi.nlm.nih.gov/pubmed/24140213References:
http://www.annalsthoracicsurgery.org/article/S0003-4975(13)01910-3/abstracthttp://en.wikipedia.org/wiki/Heart_transplantationImage: manually pumping a heart
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